Begin by shooting the orbs on the ends of the tentacles until they are gone. Do not finish her off until you have filled your bags with all the ammo and herbs you can carry. Once you are ready, head out to fight the Uroboros that Excella has now become. Do not forget the two chalices in the lockers for extra money. Once inside the tanker, scavenge any ammunition and herbs you can find. Get through the cutscene and interactive sequence. If you feel you are proficient enough with your chosen weapon, you can take only one weapon for your chosen player and leave the other character's inventory completely empty so they can carry ammo and herbs. It is recommended that you only bring one good handgun or shotgun weapon (for example, fully upgraded M92F, Jailbreaker - because ammo will be more than plentiful) each for Chris and Sheva. Start Chapter 6-2 with only the bare essentials you need to survive. Efficient ammo, grenade, and herb farming.Note: You do not need to purchase the infinite ammo in 'Bonus Features' as you would do for normal guns. Attempting this with a friend instead of the CPU-controlled Sheva is recommended. Also, avoid any crates, barrels, or treasures. Only kill story-driven enemies (ones that hold key cards or those that must be defeated to advance the game). A really easy way of doing this is to play under the Amateur difficulty setting and just run pass all enemies. Use the following trick to get a combined clear time for the entire game of under five hours (to unlock unlimited RPG ammunition). This may require a few attempts and more than one shotgun blast. You must within melee range for the icon to appear. You will stab them in the heart with a knife. Fire a shotgun at point blank range until it falls over on its back, and the quick time event icon appears to perform a finishing move. Play Chapter 5-1 as Chris or Sheva under the easy difficulty setting and encounter the first Licker. The name for the virus in Resident Evil 5, Uroboros, is also used as a name for the corporation in Devil May Cry 2, another Capcom game.

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